Vitamin B2

Vitamin B2, as a precursor of FAD and FMN, participates in redox reactions and energy metabolism:

• Energy metabolism: As an electron carrier, it participates in the mitochondrial electron transport chain (complexes I and II) and fatty acid beta oxidation.
• Antioxidant effect: Maintaining the intracellular antioxidant system through glutathione reductase (FAD dependent).
• Deficiency syndrome: leading to angular inflammation, dry lips, glossitis ("oral reproductive syndrome"), and corneal vascular hyperplasia.
• Clinical application: Treatment of migraine (high-dose can reduce the frequency of attacks), prevention of riboflavin deficiency, and as a phototherapy adjuvant (neonatal jaundice).